The film's rough cut premiered on March 14, 2016, at South by Southwest, followed by its general theatrical release in the United States on August 12, 2016, by Columbia Pictures. It is the first computer-animated film to be rated R by the Motion Picture Association of America (MPAA). The film's animation was handled by the Vancouver-based Nitrogen Studios.

The film follows an anthropomorphic sausage who lives in a supermarket and discovers the truth about what happens when groceries are purchased leading him on a journey with his friends to escape their fate while also facing a lunatic and malicious douche who wants to kill him.

It stars the voices of Rogen (in a dual role), Kristen Wiig, Hill, Bill Hader (in a triple role), Michael Cera, James Franco, Danny McBride, Craig Robinson, Paul Rudd, Nick Kroll, David Krumholtz, Edward Norton, and Salma Hayek with Meat Loaf in his final film. Sausage Party is a 2016 adult animated comedy film directed by Conrad Vernon and Greg Tiernan and written by Kyle Hunter, Ariel Shaffir, Seth Rogen, and Evan Goldberg from a story by Rogen, Goldberg, and Jonah Hill.